Mass Accuracy

Analyzer Calibration

Internal calibrants infused alongside sample streams correct instantaneous mass drift caused by power supply variations or room temperature shifts. External calibration algorithms construct mass calibration curves across wide mass ranges before batch analysis begins. Lock mass corrections adjust calibration equations continuously using known reference ion signals.

Molecular Identification

Errors below five parts per million rule out candidate elemental formulas, pinpointing exact structural configurations for unknown polymer extractables. Isotopic patterns combined with precise mass values resolve nitrogen rule ambiguity and double bond equivalent calculations. Tandem mass fragmentation spectra confirm structural assignments for complex plasticizer isomers.

Drift Control

Thermal stabilization of mass analyzer flight tubes prevents physical dimension changes that alter ion arrival times. Space-charge accumulation inside ion traps degrades mass measurement precision when sample ions overload the trap volume. Automatic gain control systems regulate ion accumulation times, preserving linear response and sub-ppm precision.